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Protective Properties of FOXO1 Inhibition in a Murine Model of Non-alcoholic Fatty Liver Disease Are Associated With Attenuation of ER Stress and Necroptosis

AIM: The pathogenesis of non-alcoholic fatty liver disease is currently unclear, however, lipid accumulation leading to endoplasmic reticulum stress appears to be pivotal in the process. At present, FOXO1 is known to be involved in NAFLD progression. The relationship between necroptosis and non-alco...

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Detalles Bibliográficos
Autores principales:	Ding, Hao-ran, Tang, Zhen-ting, Tang, Ning, Zhu, Zheng-yi, Liu, Han-yi, Pan, Chen-yan, Hu, An-yin, Lin, Yun-zhen, Gou, Peng, Yuan, Xian-wen, Cai, Jia-hui, Dong, Chun-long, Wang, Jing-lin, Ren, Hao-zhen
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2020
Materias:	Physiology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7078343/ https://www.ncbi.nlm.nih.gov/pubmed/32218743 http://dx.doi.org/10.3389/fphys.2020.00177

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