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miR-22 inhibition reduces hepatic steatosis via FGF21 and FGFR1 induction
BACKGROUND & AIMS: Metabolism supports cell proliferation and growth. Surprisingly, the tumor suppressor miR-22 is induced by metabolic stimulators like bile acids. Thus, this study examines whether miR-22 could be a metabolic silencer. METHODS: The relationship between miR-22 and the expression...
| Autores principales: | , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Elsevier
2020
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7078383/ https://www.ncbi.nlm.nih.gov/pubmed/32195457 http://dx.doi.org/10.1016/j.jhepr.2020.100093 |