Sulfamoyl Heteroarylcarboxylic Acids as Promising Metallo-β-Lactamase Inhibitors for Controlling Bacterial Carbapenem Resistance

Production of metallo-β-lactamases (MBLs), which hydrolyze carbapenems, is a cause of carbapenem resistance in Enterobacteriaceae. Development of effective inhibitors for MBLs is one approach to restore carbapenem efficacy in carbapenem-resistant Enterobacteriaceae (CRE). We report here that sulfamo...

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Detalles Bibliográficos
Autores principales: Wachino, Jun-ichi, Jin, Wanchun, Kimura, Kouji, Kurosaki, Hiromasa, Sato, Ayato, Arakawa, Yoshichika
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2020
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7078479/
https://www.ncbi.nlm.nih.gov/pubmed/32184250
http://dx.doi.org/10.1128/mBio.03144-19

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7078479/
https://www.ncbi.nlm.nih.gov/pubmed/32184250
http://dx.doi.org/10.1128/mBio.03144-19

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