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Phosphoric Metabolites Link Phosphate Import and Polysaccharide Biosynthesis for Candida albicans Cell Wall Maintenance

The Candida albicans high-affinity phosphate transporter Pho84 is required for normal Target of Rapamycin (TOR) signaling, oxidative stress resistance, and virulence of this fungal pathogen. It also contributes to C. albicans’ tolerance of two antifungal drug classes, polyenes and echinocandins. Ech...

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Detalles Bibliográficos
Autores principales: Liu, Ning-Ning, Acosta-Zaldívar, Maikel, Qi, Wanjun, Diray-Arce, Joann, Walker, Louise A., Kottom, Theodore J., Kelly, Rachel, Yuan, Min, Asara, John M., Lasky-Su, Jessica Ann, Levy, Ofer, Limper, Andrew H., Gow, Neil A. R., Köhler, Julia R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7078483/
https://www.ncbi.nlm.nih.gov/pubmed/32184254
http://dx.doi.org/10.1128/mBio.03225-19