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Phosphoric Metabolites Link Phosphate Import and Polysaccharide Biosynthesis for Candida albicans Cell Wall Maintenance
The Candida albicans high-affinity phosphate transporter Pho84 is required for normal Target of Rapamycin (TOR) signaling, oxidative stress resistance, and virulence of this fungal pathogen. It also contributes to C. albicans’ tolerance of two antifungal drug classes, polyenes and echinocandins. Ech...
Autores principales: | Liu, Ning-Ning, Acosta-Zaldívar, Maikel, Qi, Wanjun, Diray-Arce, Joann, Walker, Louise A., Kottom, Theodore J., Kelly, Rachel, Yuan, Min, Asara, John M., Lasky-Su, Jessica Ann, Levy, Ofer, Limper, Andrew H., Gow, Neil A. R., Köhler, Julia R. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Society for Microbiology
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7078483/ https://www.ncbi.nlm.nih.gov/pubmed/32184254 http://dx.doi.org/10.1128/mBio.03225-19 |
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