Comparison of autophagy inducibility in various tyrosine kinase inhibitors and their enhanced cytotoxicity via inhibition of autophagy in cancer cells in combined treatment with azithromycin

Tyrosine kinase inhibitors (TKIs) induce autophagy in many types of cancer cells. We previously reported that gefitinib (GEF) and imatinib (IMA) induce autophagy in epidermal growth factor receptor (EGFR) knock-out A549 and non-BCR-ABL-expressing leukemia cell lines, respectively. This evidence sugg...

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Detalles Bibliográficos
Autores principales: Tanaka, Hideki, Hino, Hirotsugu, Moriya, Shota, Kazama, Hiromi, Miyazaki, Masaya, Takano, Naoharu, Hiramoto, Masaki, Tsukahara, Kiyoaki, Miyazawa, Keisuke
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2020
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7078496/
https://www.ncbi.nlm.nih.gov/pubmed/32195376
http://dx.doi.org/10.1016/j.bbrep.2020.100750

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