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S100 Soil Sensor Receptors and Molecular Targeting Therapy Against Them in Cancer Metastasis
The molecular mechanisms underlying the ‘seed and soil’ theory are unknown. S100A8/A9 (a heterodimer complex of S100A8 and S100A9 proteins that exhibits a ‘soil signal’) is a ligand for Toll-like receptor 4, causing distant melanoma cells to approach the lung as a ‘seeding’ site. Unknown soil sensor...
| Autores principales: | , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Neoplasia Press
2020
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7078545/ https://www.ncbi.nlm.nih.gov/pubmed/32193075 http://dx.doi.org/10.1016/j.tranon.2020.100753 |