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Krüppel-like Factor 5 Regulates Stemness, Lineage Specification, and Regeneration of Intestinal Epithelial Stem Cells

BACKGROUND & AIMS: Self-renewal and multipotent differentiation are cardinal properties of intestinal stem cells (ISCs), mediated in part by WNT and NOTCH signaling. Although these pathways are well characterized, the molecular mechanisms that control the ‘stemness’ of ISCs are still not well de...

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Detalles Bibliográficos
Autores principales: Kim, Chang-Kyung, Saxena, Madhurima, Maharjan, Kasmika, Song, Jane J., Shroyer, Kenneth R., Bialkowska, Agnieszka B., Shivdasani, Ramesh A., Yang, Vincent W.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7078555/
https://www.ncbi.nlm.nih.gov/pubmed/31778829
http://dx.doi.org/10.1016/j.jcmgh.2019.11.009

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