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Krüppel-like Factor 5 Regulates Stemness, Lineage Specification, and Regeneration of Intestinal Epithelial Stem Cells
BACKGROUND & AIMS: Self-renewal and multipotent differentiation are cardinal properties of intestinal stem cells (ISCs), mediated in part by WNT and NOTCH signaling. Although these pathways are well characterized, the molecular mechanisms that control the ‘stemness’ of ISCs are still not well de...
Autores principales: | Kim, Chang-Kyung, Saxena, Madhurima, Maharjan, Kasmika, Song, Jane J., Shroyer, Kenneth R., Bialkowska, Agnieszka B., Shivdasani, Ramesh A., Yang, Vincent W. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7078555/ https://www.ncbi.nlm.nih.gov/pubmed/31778829 http://dx.doi.org/10.1016/j.jcmgh.2019.11.009 |
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