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Early-onset dementia: diagnostic challenges
A 56-year-old man was brought to our hospital by his family, seeking medical treatment for the patient’s long-standing progressive word-finding difficulties, forgetfulness, agitation and social withdrawal. After multiple previous physician consultations, the patient was mistakenly diagnosed with epi...
Autores principales: | , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BMJ Publishing Group
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7078668/ https://www.ncbi.nlm.nih.gov/pubmed/32188610 http://dx.doi.org/10.1136/bcr-2019-233460 |
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author | Elhusein, Bushra Mahgoub, Omer Bakri Khairi, Abdalla |
author_facet | Elhusein, Bushra Mahgoub, Omer Bakri Khairi, Abdalla |
author_sort | Elhusein, Bushra |
collection | PubMed |
description | A 56-year-old man was brought to our hospital by his family, seeking medical treatment for the patient’s long-standing progressive word-finding difficulties, forgetfulness, agitation and social withdrawal. After multiple previous physician consultations, the patient was mistakenly diagnosed with epilepsy and prescribed multiple anticonvulsants, to which his above mentioned symptoms were unresponsive. His condition progressed over the next 10 years, resulting in severe cognitive impairments and a complete dysfunctionality. An electroencephalogram (EEG) assessment revealed persistent spike and wave activity in the left temporal lobe. Brain MRI revealed multiple small bright T2 and fluid attenuated inversion recovery (FLAIR) foci within the white matter of both cerebral hemispheres surrounding the ventricular system, as well as some widening of extra-axial cerebrospinal fluid spaces. The patient was finally diagnosed with early-onset dementia and temporal lobe epileptiform abnormalities. This case emphasises the need for diagnostic consideration of dementia in cognitively impaired patients, even when they are not of an advanced age. |
format | Online Article Text |
id | pubmed-7078668 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2020 |
publisher | BMJ Publishing Group |
record_format | MEDLINE/PubMed |
spelling | pubmed-70786682020-03-23 Early-onset dementia: diagnostic challenges Elhusein, Bushra Mahgoub, Omer Bakri Khairi, Abdalla BMJ Case Rep Unusual Presentation of More Common Disease/Injury A 56-year-old man was brought to our hospital by his family, seeking medical treatment for the patient’s long-standing progressive word-finding difficulties, forgetfulness, agitation and social withdrawal. After multiple previous physician consultations, the patient was mistakenly diagnosed with epilepsy and prescribed multiple anticonvulsants, to which his above mentioned symptoms were unresponsive. His condition progressed over the next 10 years, resulting in severe cognitive impairments and a complete dysfunctionality. An electroencephalogram (EEG) assessment revealed persistent spike and wave activity in the left temporal lobe. Brain MRI revealed multiple small bright T2 and fluid attenuated inversion recovery (FLAIR) foci within the white matter of both cerebral hemispheres surrounding the ventricular system, as well as some widening of extra-axial cerebrospinal fluid spaces. The patient was finally diagnosed with early-onset dementia and temporal lobe epileptiform abnormalities. This case emphasises the need for diagnostic consideration of dementia in cognitively impaired patients, even when they are not of an advanced age. BMJ Publishing Group 2020-03-17 /pmc/articles/PMC7078668/ /pubmed/32188610 http://dx.doi.org/10.1136/bcr-2019-233460 Text en © BMJ Publishing Group Limited 2020. Re-use permitted under CC BY-NC. No commercial re-use. See rights and permissions. Published by BMJ. http://creativecommons.org/licenses/by-nc/4.0/This is an open access article distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/. |
spellingShingle | Unusual Presentation of More Common Disease/Injury Elhusein, Bushra Mahgoub, Omer Bakri Khairi, Abdalla Early-onset dementia: diagnostic challenges |
title | Early-onset dementia: diagnostic challenges |
title_full | Early-onset dementia: diagnostic challenges |
title_fullStr | Early-onset dementia: diagnostic challenges |
title_full_unstemmed | Early-onset dementia: diagnostic challenges |
title_short | Early-onset dementia: diagnostic challenges |
title_sort | early-onset dementia: diagnostic challenges |
topic | Unusual Presentation of More Common Disease/Injury |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7078668/ https://www.ncbi.nlm.nih.gov/pubmed/32188610 http://dx.doi.org/10.1136/bcr-2019-233460 |
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