Cargando…

Endovascular repair during complex thoracic aortic dissection using a micropore stent graft: Midterm follow‐up clinical outcomes

OBJECTIVE: This study explored the clinical efficacy and hemodynamic effects of the micropore stent graft (MSG) that could promote aortic remodeling and preserve important organ branches. METHODS: We conducted a retrospective analysis of 26 patients who underwent endovascular repair using an MSG for...

Descripción completa

Detalles Bibliográficos
Autores principales: Wang, Zhe, Wang, Cheng, Li, Fenghe, Zhao, Yu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley & Sons, Inc. 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7078903/
https://www.ncbi.nlm.nih.gov/pubmed/31408266
http://dx.doi.org/10.1002/ccd.28437
_version_ 1783507715240230912
author Wang, Zhe
Wang, Cheng
Li, Fenghe
Zhao, Yu
author_facet Wang, Zhe
Wang, Cheng
Li, Fenghe
Zhao, Yu
author_sort Wang, Zhe
collection PubMed
description OBJECTIVE: This study explored the clinical efficacy and hemodynamic effects of the micropore stent graft (MSG) that could promote aortic remodeling and preserve important organ branches. METHODS: We conducted a retrospective analysis of 26 patients who underwent endovascular repair using an MSG for DeBakey types I and III TAD at our center between December 2014 and December 2017. The main efficacy parameters were rupture of the false lumen or dissection‐related death, conversion to open repair, secondary reintervention, branch vessel patency, and the hemodynamic effects of TAD at 12 months. RESULTS: Dissection rupture, dissection‐related mortality, conversion to open repair, and secondary reintervention rates at 12 months were 0, 3.9, 0, and 0%, respectively. In the 24 patients with more than 6 months of follow‐up, micropore stents were implanted to cover 39 openings in aortic arch branches, 91.7% (22/24) presented with complete thrombosis in the false lumen, 8.3% (2/24) presented with partial thrombosis in the false lumen, 35.2% (6/17) presented with a thrombus in the false lumen that was completely absorbed, and all 39 branches were patent. After surgery, pressure peak value and fluctuation along with the degree and range of unstable blood flow in the aortic lumen decreased. CONCLUSIONS: For type I and type III thoracic artic dissection, endovascular treatment with an MSG may be a safe and effective treatment option with a good midterm outcome.
format Online
Article
Text
id pubmed-7078903
institution National Center for Biotechnology Information
language English
publishDate 2019
publisher John Wiley & Sons, Inc.
record_format MEDLINE/PubMed
spelling pubmed-70789032020-03-19 Endovascular repair during complex thoracic aortic dissection using a micropore stent graft: Midterm follow‐up clinical outcomes Wang, Zhe Wang, Cheng Li, Fenghe Zhao, Yu Catheter Cardiovasc Interv Peripheral Vascular Disease OBJECTIVE: This study explored the clinical efficacy and hemodynamic effects of the micropore stent graft (MSG) that could promote aortic remodeling and preserve important organ branches. METHODS: We conducted a retrospective analysis of 26 patients who underwent endovascular repair using an MSG for DeBakey types I and III TAD at our center between December 2014 and December 2017. The main efficacy parameters were rupture of the false lumen or dissection‐related death, conversion to open repair, secondary reintervention, branch vessel patency, and the hemodynamic effects of TAD at 12 months. RESULTS: Dissection rupture, dissection‐related mortality, conversion to open repair, and secondary reintervention rates at 12 months were 0, 3.9, 0, and 0%, respectively. In the 24 patients with more than 6 months of follow‐up, micropore stents were implanted to cover 39 openings in aortic arch branches, 91.7% (22/24) presented with complete thrombosis in the false lumen, 8.3% (2/24) presented with partial thrombosis in the false lumen, 35.2% (6/17) presented with a thrombus in the false lumen that was completely absorbed, and all 39 branches were patent. After surgery, pressure peak value and fluctuation along with the degree and range of unstable blood flow in the aortic lumen decreased. CONCLUSIONS: For type I and type III thoracic artic dissection, endovascular treatment with an MSG may be a safe and effective treatment option with a good midterm outcome. John Wiley & Sons, Inc. 2019-08-13 2020-03-01 /pmc/articles/PMC7078903/ /pubmed/31408266 http://dx.doi.org/10.1002/ccd.28437 Text en © 2019 The Authors. Catheterization and Cardiovascular Interventions published by Wiley Periodicals, Inc. This is an open access article under the terms of the http://creativecommons.org/licenses/by-nc/4.0/ License, which permits use, distribution and reproduction in any medium, provided the original work is properly cited and is not used for commercial purposes.
spellingShingle Peripheral Vascular Disease
Wang, Zhe
Wang, Cheng
Li, Fenghe
Zhao, Yu
Endovascular repair during complex thoracic aortic dissection using a micropore stent graft: Midterm follow‐up clinical outcomes
title Endovascular repair during complex thoracic aortic dissection using a micropore stent graft: Midterm follow‐up clinical outcomes
title_full Endovascular repair during complex thoracic aortic dissection using a micropore stent graft: Midterm follow‐up clinical outcomes
title_fullStr Endovascular repair during complex thoracic aortic dissection using a micropore stent graft: Midterm follow‐up clinical outcomes
title_full_unstemmed Endovascular repair during complex thoracic aortic dissection using a micropore stent graft: Midterm follow‐up clinical outcomes
title_short Endovascular repair during complex thoracic aortic dissection using a micropore stent graft: Midterm follow‐up clinical outcomes
title_sort endovascular repair during complex thoracic aortic dissection using a micropore stent graft: midterm follow‐up clinical outcomes
topic Peripheral Vascular Disease
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7078903/
https://www.ncbi.nlm.nih.gov/pubmed/31408266
http://dx.doi.org/10.1002/ccd.28437
work_keys_str_mv AT wangzhe endovascularrepairduringcomplexthoracicaorticdissectionusingamicroporestentgraftmidtermfollowupclinicaloutcomes
AT wangcheng endovascularrepairduringcomplexthoracicaorticdissectionusingamicroporestentgraftmidtermfollowupclinicaloutcomes
AT lifenghe endovascularrepairduringcomplexthoracicaorticdissectionusingamicroporestentgraftmidtermfollowupclinicaloutcomes
AT zhaoyu endovascularrepairduringcomplexthoracicaorticdissectionusingamicroporestentgraftmidtermfollowupclinicaloutcomes