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Oxidative stress‐alleviating strategies to improve recombinant protein production in CHO cells

Large scale biopharmaceutical production of biologics relies on the overexpression of foreign proteins by cells cultivated in stirred tank bioreactors. It is well recognized and documented fact that protein overexpression may impact host cell metabolism and that factors associated with large scale c...

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Detalles Bibliográficos
Autores principales:	Chevallier, Valentine, Andersen, Mikael Rørdam, Malphettes, Laetitia
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	John Wiley and Sons Inc. 2019
Materias:	REVIEWS
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7078918/ https://www.ncbi.nlm.nih.gov/pubmed/31814104 http://dx.doi.org/10.1002/bit.27247

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