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Activated microglia desialylate their surface, stimulating complement receptor 3‐mediated phagocytosis of neurons
The glycoproteins and glycolipids of the cell surface have sugar chains that normally terminate in a sialic acid residue, but inflammatory activation of myeloid cells can cause sialidase enzymes to remove these residues, resulting in desialylation and altered activity of surface receptors, such as t...
| Autores principales: | , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
John Wiley & Sons, Inc.
2019
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7079032/ https://www.ncbi.nlm.nih.gov/pubmed/31774586 http://dx.doi.org/10.1002/glia.23757 |