Dysregulation of the actin scavenging system and inhibition of DNase activity following severe thermal injury

BACKGROUND: Circulating cell‐free DNA (cfDNA) is not found in healthy subjects, but is readily detected after thermal injury and may contribute to the risk of multiple organ failure. The hypothesis was that a postburn reduction in DNase protein/enzyme activity could contribute to the increase in cfD...

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Detalles Bibliográficos
Autores principales: Dinsdale, R. J., Hazeldine, J., Al Tarrah, K., Hampson, P., Devi, A., Ermogenous, C., Bamford, A. L., Bishop, J., Watts, S., Kirkman, E., Dalle Lucca, J. J., Midwinter, M., Woolley, T., Foster, M., Lord, J. M., Moiemen, N., Harrison, P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley & Sons, Ltd 2019
Materias:
Original Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7079039/
https://www.ncbi.nlm.nih.gov/pubmed/31502663
http://dx.doi.org/10.1002/bjs.11310

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