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Carcinoembryonic antigen‐specific, fluorescent image‐guided cytoreductive surgery with hyperthermic intraperitoneal chemotherapy for metastatic colorectal cancer
This multicentre pilot study investigated the role of peroperative carcinoembryonic antigen (CEA)‐specific fluorescence imaging during cytoreductive surgery–hyperthermic intraperitoneal chemotherapy surgery in peritoneal metastasized colorectal cancer. A correct change in peritoneal carcinomatosis i...
| Autores principales: | , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
John Wiley & Sons, Ltd
2020
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7079046/ https://www.ncbi.nlm.nih.gov/pubmed/31960953 http://dx.doi.org/10.1002/bjs.11523 |
| _version_ | 1783507747465068544 |
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| author | Schaap, D. P. de Valk, K. S. Deken, M. M. Meijer, R. P. J. Burggraaf, J. Vahrmeijer, A. L. Kusters, M. |
| author_facet | Schaap, D. P. de Valk, K. S. Deken, M. M. Meijer, R. P. J. Burggraaf, J. Vahrmeijer, A. L. Kusters, M. |
| author_sort | Schaap, D. P. |
| collection | PubMed |
| description | This multicentre pilot study investigated the role of peroperative carcinoembryonic antigen (CEA)‐specific fluorescence imaging during cytoreductive surgery–hyperthermic intraperitoneal chemotherapy surgery in peritoneal metastasized colorectal cancer. A correct change in peritoneal carcinomatosis index (PCI) owing to fluorescence imaging was seen in four of the 14 included patients. The use of SGM‐101 in patients with peritoneally metastasized colorectal carcinoma is feasible, and allows intraoperative detection of tumour deposits and alteration of the PCI.[Image: see text] Augmented reality guidance |
| format | Online Article Text |
| id | pubmed-7079046 |
| institution | National Center for Biotechnology Information |
| language | English |
| publishDate | 2020 |
| publisher | John Wiley & Sons, Ltd |
| record_format | MEDLINE/PubMed |
| spelling | pubmed-70790462020-03-19 Carcinoembryonic antigen‐specific, fluorescent image‐guided cytoreductive surgery with hyperthermic intraperitoneal chemotherapy for metastatic colorectal cancer Schaap, D. P. de Valk, K. S. Deken, M. M. Meijer, R. P. J. Burggraaf, J. Vahrmeijer, A. L. Kusters, M. Br J Surg Rapid Research Communication This multicentre pilot study investigated the role of peroperative carcinoembryonic antigen (CEA)‐specific fluorescence imaging during cytoreductive surgery–hyperthermic intraperitoneal chemotherapy surgery in peritoneal metastasized colorectal cancer. A correct change in peritoneal carcinomatosis index (PCI) owing to fluorescence imaging was seen in four of the 14 included patients. The use of SGM‐101 in patients with peritoneally metastasized colorectal carcinoma is feasible, and allows intraoperative detection of tumour deposits and alteration of the PCI.[Image: see text] Augmented reality guidance John Wiley & Sons, Ltd 2020-01-21 2020-03 /pmc/articles/PMC7079046/ /pubmed/31960953 http://dx.doi.org/10.1002/bjs.11523 Text en © 2020 The Authors. BJS published by John Wiley & Sons Ltd on behalf of BJS Society Ltd. This is an open access article under the terms of the http://creativecommons.org/licenses/by-nc-nd/4.0/ License, which permits use and distribution in any medium, provided the original work is properly cited, the use is non‐commercial and no modifications or adaptations are made. |
| spellingShingle | Rapid Research Communication Schaap, D. P. de Valk, K. S. Deken, M. M. Meijer, R. P. J. Burggraaf, J. Vahrmeijer, A. L. Kusters, M. Carcinoembryonic antigen‐specific, fluorescent image‐guided cytoreductive surgery with hyperthermic intraperitoneal chemotherapy for metastatic colorectal cancer |
| title | Carcinoembryonic antigen‐specific, fluorescent image‐guided cytoreductive surgery with hyperthermic intraperitoneal chemotherapy for metastatic colorectal cancer |
| title_full | Carcinoembryonic antigen‐specific, fluorescent image‐guided cytoreductive surgery with hyperthermic intraperitoneal chemotherapy for metastatic colorectal cancer |
| title_fullStr | Carcinoembryonic antigen‐specific, fluorescent image‐guided cytoreductive surgery with hyperthermic intraperitoneal chemotherapy for metastatic colorectal cancer |
| title_full_unstemmed | Carcinoembryonic antigen‐specific, fluorescent image‐guided cytoreductive surgery with hyperthermic intraperitoneal chemotherapy for metastatic colorectal cancer |
| title_short | Carcinoembryonic antigen‐specific, fluorescent image‐guided cytoreductive surgery with hyperthermic intraperitoneal chemotherapy for metastatic colorectal cancer |
| title_sort | carcinoembryonic antigen‐specific, fluorescent image‐guided cytoreductive surgery with hyperthermic intraperitoneal chemotherapy for metastatic colorectal cancer |
| topic | Rapid Research Communication |
| url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7079046/ https://www.ncbi.nlm.nih.gov/pubmed/31960953 http://dx.doi.org/10.1002/bjs.11523 |
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