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Supramolecular clustering of the cardiac sodium channel Nav1.5 in HEK293F cells, with and without the auxiliary β3‐subunit

Voltage‐gated sodium channels comprise an ion‐selective α‐subunit and one or more associated β‐subunits. The β3‐subunit (encoded by the SCN3B gene) is an important physiological regulator of the heart‐specific sodium channel, Nav1.5. We have previously shown that when expressed alone in HEK293F cell...

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Detalles Bibliográficos
Autores principales: Salvage, Samantha C., Rees, Johanna S., McStea, Alexandra, Hirsch, Michael, Wang, Lin, Tynan, Christopher J., Reed, Matthew W., Irons, Jennifer R., Butler, Richard, Thompson, Andrew J., Martin-Fernandez, Marisa L., Huang, Christopher L.‐H., Jackson, Antony P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7079131/
https://www.ncbi.nlm.nih.gov/pubmed/31950564
http://dx.doi.org/10.1096/fj.201701473RR

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