Alum impairs tolerogenic properties induced by allergoid‐mannan conjugates inhibiting mTOR and metabolic reprogramming in human DCs

BACKGROUND: Polymerized allergoids conjugated to mannan (PM) are suitable vaccines for allergen‐specific immunotherapy (AIT). Alum remains the most widely used adjuvant in AIT, but its way of action is not completely elucidated. The better understanding of the mechanisms underlying alum adjuvanticit...

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Detalles Bibliográficos
Autores principales: Benito‐Villalvilla, Cristina, Soria, Irene, Pérez‐Diego, Mario, Fernández‐Caldas, Enrique, Subiza, José Luis, Palomares, Oscar
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2019
Materias:
ORIGINAL ARTICLES
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7079174/
https://www.ncbi.nlm.nih.gov/pubmed/31494959
http://dx.doi.org/10.1111/all.14036

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7079174/
https://www.ncbi.nlm.nih.gov/pubmed/31494959
http://dx.doi.org/10.1111/all.14036

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