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Cerebrospinal Fluid Characterization in Cynomolgus Monkeys, Beagle Dogs, and Göttingen Minipigs
Intrathecal administration is an important route for drug delivery, and in pharmacology and toxicology studies, cerebrospinal fluid (CSF) collection and analysis is required for evaluating blood–brain barrier penetration and central nervous system exposure. The characteristics of CSF in commonly use...
Autores principales: | Ballesteros, Cristina, Pouliot, Mylène, Froment, Rémi, Maghezzi, Mohamed Said, St-Jean, Camille, Li, Christian, Paquette, Dominique, Authier, Simon |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
SAGE Publications
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7079291/ https://www.ncbi.nlm.nih.gov/pubmed/32066300 http://dx.doi.org/10.1177/1091581820905092 |
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