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Cerebrospinal Fluid Characterization in Cynomolgus Monkeys, Beagle Dogs, and Göttingen Minipigs

Intrathecal administration is an important route for drug delivery, and in pharmacology and toxicology studies, cerebrospinal fluid (CSF) collection and analysis is required for evaluating blood–brain barrier penetration and central nervous system exposure. The characteristics of CSF in commonly use...

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Detalles Bibliográficos
Autores principales: Ballesteros, Cristina, Pouliot, Mylène, Froment, Rémi, Maghezzi, Mohamed Said, St-Jean, Camille, Li, Christian, Paquette, Dominique, Authier, Simon
Formato: Online Artículo Texto
Lenguaje:English
Publicado: SAGE Publications 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7079291/
https://www.ncbi.nlm.nih.gov/pubmed/32066300
http://dx.doi.org/10.1177/1091581820905092

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