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Modeling methylation dynamics with simultaneous changes in CpG islands
BACKGROUND: In vertebrate genomes, CpG sites can be clustered into CpG islands, and the amount of methylation in a CpG island can change due to gene regulation processes. Thus, single regulatory events can simultaneously change the methylation states of many CpG sites within a CpG island. This shoul...
| Autores principales: | , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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BioMed Central
2020
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7079395/ https://www.ncbi.nlm.nih.gov/pubmed/32183713 http://dx.doi.org/10.1186/s12859-020-3438-5 |