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Severe sepsis caused by serious gastrointestinal infection in sJIA patients treated with IL-6 receptor antagonist: a case report

BACKGROUND: Interleukin (IL)-6 plays an essential role in the pathogenesis of systemic juvenile idiopathic arthritis (sJIA). Tocilizumab (TCZ), a kind of biological agent against both membrane and soluble IL-6 receptor, is the only biological agent approved for the treatment of sJIA in China. Infect...

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Detalles Bibliográficos
Autores principales: Xu, Meng, Liu, Congcong, Guo, Lishuang, Yang, Sirui
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7079483/
https://www.ncbi.nlm.nih.gov/pubmed/32188441
http://dx.doi.org/10.1186/s12887-020-02032-w