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Conditional Dnmt3b deletion in hippocampal dCA1 impairs recognition memory

AIM: Active changes in neuronal DNA methylation and demethylation appear to act as controllers of synaptic scaling and glutamate receptor trafficking in learning and memory formation. DNA methyltransferases (DNMTs), including proteins encoded by Dnmt1, Dnmt3a and Dnmt3b, are dominant enzymes carryin...

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Detalles Bibliográficos
Autores principales: Kong, Qingnuan, Yu, Ming, Zhang, Meng, Wei, Chuang, Gu, Huating, Yu, Shaoyang, Sun, Wei, Li, Nan, Zhou, Yu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7079487/
https://www.ncbi.nlm.nih.gov/pubmed/32183852
http://dx.doi.org/10.1186/s13041-020-00574-9

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