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Tumor burden is a potential marker of PARP inhibitor effects in ovarian cancer: a head-to-head observational series
BACKGROUND: Olaparib, a poly ADP-ribose polymerase (PARP) inhibitor, has proven to be effective and safe as maintenance therapy and multiline therapy in ovarian cancer, especially in patients with BRCA mutations. This study intended to observe the influence of tumor load on the efficacy and safety o...
Autores principales: | Ni, Jing, Zhou, Rui, Cheng, Xianzhong, Xu, Xia, Guo, Wenwen, Chen, Xiaoxiang |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7079537/ https://www.ncbi.nlm.nih.gov/pubmed/32183851 http://dx.doi.org/10.1186/s13048-020-00629-4 |
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