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Deletion of accessory genes 3a, 3b, 5a or 5b from avian coronavirus infectious bronchitis virus induces an attenuated phenotype both in vitro and in vivo

Avian coronavirus infectious bronchitis virus (IBV) infects domestic fowl, resulting in respiratory disease and causing serious losses in unprotected birds. Its control is mainly achieved by using live attenuated vaccines. Here we explored the possibilities for rationally attenuating IBV to improve...

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Detalles Bibliográficos
Autores principales:	Laconi, Andrea, van Beurden, Steven J., Berends, Alinda J., Krämer-Kühl, Annika, Jansen, Christine A., Spekreijse, Dieuwertje, Chénard, Gilles, Philipp, Hans-Christian, Mundt, Egbert, Rottier, Peter J. M., Hélène Verheije, M.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Microbiology Society 2018
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7079694/ https://www.ncbi.nlm.nih.gov/pubmed/30067172 http://dx.doi.org/10.1099/jgv.0.001130

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