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Saikosaponin C exerts anti-HBV effects by attenuating HNF1α and HNF4α expression to suppress HBV pgRNA synthesis

OBJECTIVE: Saikosaponin c (SSc), a compound purified from the traditional Chinese herb of Radix Bupleuri was previously identified to exhibit anti-HBV replication activity. However, the mechanism through which SSc acts against HBV remains unknown. In this study, we investigated the mechanism of SSc...

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Detalles Bibliográficos
Autores principales: Pan, Yanchao, Ke, Zhiyi, Ye, Hong, Sun, Lina, Ding, Xiaoyan, Shen, Yun, Zhang, Runze, Yuan, Jing
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer International Publishing 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7079752/
https://www.ncbi.nlm.nih.gov/pubmed/31531682
http://dx.doi.org/10.1007/s00011-019-01284-2