Cargando…
Saikosaponin C exerts anti-HBV effects by attenuating HNF1α and HNF4α expression to suppress HBV pgRNA synthesis
OBJECTIVE: Saikosaponin c (SSc), a compound purified from the traditional Chinese herb of Radix Bupleuri was previously identified to exhibit anti-HBV replication activity. However, the mechanism through which SSc acts against HBV remains unknown. In this study, we investigated the mechanism of SSc...
Autores principales: | Pan, Yanchao, Ke, Zhiyi, Ye, Hong, Sun, Lina, Ding, Xiaoyan, Shen, Yun, Zhang, Runze, Yuan, Jing |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Springer International Publishing
2019
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7079752/ https://www.ncbi.nlm.nih.gov/pubmed/31531682 http://dx.doi.org/10.1007/s00011-019-01284-2 |
Ejemplares similares
-
Measuring hepatitis B pgRNA stability using an updated automated HBV pgRNA assay with increased sensitivity
por: Anderson, Mark, et al.
Publicado: (2023) -
RNA binding protein TIAR modulates HBV replication by tipping the balance of pgRNA translation
por: Zhang, Ting, et al.
Publicado: (2023) -
HBV pgRNA profiles in Chinese HIV/HBV coinfected patients under pre‐ and posttreatment: a multicentre observational cohort study
por: Xu, Ling, et al.
Publicado: (2022) -
Neddylation inhibitor MLN4924 has anti‐HBV activity via modulating the ERK‐HNF1α‐C/EBPα‐HNF4α axis
por: Xie, Mingjie, et al.
Publicado: (2020) -
TRIM25 inhibits HBV replication by promoting HBx degradation and the RIG-I-mediated pgRNA recognition
por: Song, Hongxiao, et al.
Publicado: (2023)