The SARS-CoV S glycoprotein

The severe acute respiratory syndrome-coronavirus (SARS-CoV) spike (S) glycoprotein alone can mediate the membrane fusion required for virus entry and cell fusion. It is also a major immunogen and a target for entry inhibitors. Recent rapid advances in our knowledge of the structure and function of...

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Detalles Bibliográficos
Autores principales: Xiao, X., Dimitrov, D. S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Birkhäuser-Verlag 2004
Materias:
Visions & Reflections
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7079772/
https://www.ncbi.nlm.nih.gov/pubmed/15526150
http://dx.doi.org/10.1007/s00018-004-4257-y
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author Xiao, X.
Dimitrov, D. S.
author_facet Xiao, X.
Dimitrov, D. S.
author_sort Xiao, X.
collection PubMed
description The severe acute respiratory syndrome-coronavirus (SARS-CoV) spike (S) glycoprotein alone can mediate the membrane fusion required for virus entry and cell fusion. It is also a major immunogen and a target for entry inhibitors. Recent rapid advances in our knowledge of the structure and function of this protein have lead to the development of a number of candidate vaccine immunogens and SARS-CoV entry inhibitors.
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spelling pubmed-70797722020-03-23 The SARS-CoV S glycoprotein Xiao, X. Dimitrov, D. S. Cell Mol Life Sci Visions & Reflections The severe acute respiratory syndrome-coronavirus (SARS-CoV) spike (S) glycoprotein alone can mediate the membrane fusion required for virus entry and cell fusion. It is also a major immunogen and a target for entry inhibitors. Recent rapid advances in our knowledge of the structure and function of this protein have lead to the development of a number of candidate vaccine immunogens and SARS-CoV entry inhibitors. Birkhäuser-Verlag 2004 /pmc/articles/PMC7079772/ /pubmed/15526150 http://dx.doi.org/10.1007/s00018-004-4257-y Text en © Birkhäuser Verlag, Basel 2004 This article is made available via the PMC Open Access Subset for unrestricted research re-use and secondary analysis in any form or by any means with acknowledgement of the original source. These permissions are granted for the duration of the World Health Organization (WHO) declaration of COVID-19 as a global pandemic.
spellingShingle Visions & Reflections
Xiao, X.
Dimitrov, D. S.
The SARS-CoV S glycoprotein
title The SARS-CoV S glycoprotein
title_full The SARS-CoV S glycoprotein
title_fullStr The SARS-CoV S glycoprotein
title_full_unstemmed The SARS-CoV S glycoprotein
title_short The SARS-CoV S glycoprotein
title_sort sars-cov s glycoprotein
topic Visions & Reflections
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7079772/
https://www.ncbi.nlm.nih.gov/pubmed/15526150
http://dx.doi.org/10.1007/s00018-004-4257-y
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