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Overexpression of HAb18G/CD147 promotes invasion and metastasis via α3β1 integrin mediated FAK-paxillin and FAK-PI3K-Ca(2+) pathways

Mechanism of HAb18G/CD147 underlying the metastasis process of human hepatoma cells has not been determined. In the present study, we found that integrin α3β1 colocalizes with HAb18G/CD147 in human 7721 hepatoma cells. The enhancing effect of HAb18G/CD147 on adhesion, invasion capacities and matrix...

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Detalles Bibliográficos
Autores principales: Tang, J., Wu, Y.-M., Zhao, P., Yang, X.-M., Jiang, J.-L., Chen, Z.-N.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: SP Birkhäuser Verlag Basel 2008
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7079791/
https://www.ncbi.nlm.nih.gov/pubmed/18695939
http://dx.doi.org/10.1007/s00018-008-8315-8

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