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Depletion of angiotensin-converting enzyme 2 reduces brain serotonin and impairs the running-induced neurogenic response
Physical exercise induces cell proliferation in the adult hippocampus in rodents. Serotonin (5-HT) and angiotensin (Ang) II are important mediators of the pro-mitotic effect of physical activity. Here, we examine precursor cells in the adult brain of mice lacking angiotensin-converting enzyme (ACE)...
Autores principales: | Klempin, Friederike, Mosienko, Valentina, Matthes, Susann, Villela, Daniel C., Todiras, Mihail, Penninger, Josef M., Bader, Michael, Santos, Robson A. S., Alenina, Natalia |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Springer International Publishing
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7079801/ https://www.ncbi.nlm.nih.gov/pubmed/29679094 http://dx.doi.org/10.1007/s00018-018-2815-y |
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