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Advances in anti-viral immune defence: revealing the importance of the IFN JAK/STAT pathway
Interferon-alpha (IFN-α) is a potent anti-viral cytokine, critical to the host immune response against viruses. IFN-α is first produced upon viral detection by pathogen recognition receptors. Following its expression, IFN-α embarks upon a complex downstream signalling cascade called the JAK/STAT pat...
| Autores principales: | , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Springer International Publishing
2017
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7079803/ https://www.ncbi.nlm.nih.gov/pubmed/28432378 http://dx.doi.org/10.1007/s00018-017-2520-2 |