Cargando…

The role of lipocalin-2 in age-related macular degeneration (AMD)

Lipocalins are a family of secreted adipokines which play important roles in various biological processes. Lipocalin-2 (LCN-2) has been shown to be involved in acute and chronic inflammation. This particular protein is critical in the pathogenesis of several diseases including cancer, diabetes, obes...

Descripción completa

Detalles Bibliográficos
Autores principales:	Ghosh, Sayan, Stepicheva, Nadezda, Yazdankhah, Meysam, Shang, Peng, Watson, Alan M., Hose, Stacey, Liu, Haitao, Weiss, Joseph, Zigler, J. Samuel, Valapala, Mallika, Watkins, Simon C., Sinha, Debasish
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Springer International Publishing 2020
Materias:	Review
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7079812/ https://www.ncbi.nlm.nih.gov/pubmed/31901947 http://dx.doi.org/10.1007/s00018-019-03423-8

Ejemplares similares

A Novel Method of Mouse RPE Explant Culture and Effective Introduction of Transgenes Using Adenoviral Transduction for In Vitro Studies in AMD
por: Shang, Peng, et al.
Publicado: (2021)

A Role for βA3/A1-Crystallin in Type 2 EMT of RPE Cells Occurring in Dry Age-Related Macular Degeneration
por: Ghosh, Sayan, et al.
Publicado: (2018)

Mitophagy in Astrocytes Is Required for the Health of Optic Nerve
por: Yazdankhah, Meysam, et al.
Publicado: (2023)

Neutrophils homing into the retina trigger pathology in early age-related macular degeneration
por: Ghosh, Sayan, et al.
Publicado: (2019)

Reducing Akt2 in retinal pigment epithelial cells causes a compensatory increase in Akt1 and attenuates diabetic retinopathy
por: Liu, Haitao, et al.
Publicado: (2022)

Increased Lipocalin-2 in the retinal pigment epithelium of Cryba1 cKO mice is associated with a chronic inflammatory response
por: Valapala, Mallika, et al.
Publicado: (2014)

βA3/A1-crystallin regulates apical polarity and EGFR endocytosis in retinal pigmented epithelial cells
por: Shang, Peng, et al.
Publicado: (2021)

Microglia–Neutrophil Interactions Drive Dry AMD-like Pathology in a Mouse Model
por: Boyce, Maeve, et al.
Publicado: (2022)

βA3/A1-crystallin is a critical mediator of STAT3 signaling in optic nerve astrocytes
por: Valapala, Mallika, et al.
Publicado: (2015)

Aberrant Akt2 signaling in the RPE may contribute to retinal fibrosis process in diabetic retinopathy
por: Daley, Rachel, et al.
Publicado: (2023)

βA1-crystallin regulates glucose metabolism and mitochondrial function in mouse retinal astrocytes by modulating PTP1B activity
por: Ghosh, Sayan, et al.
Publicado: (2021)

The amino acid transporter SLC36A4 regulates the amino acid pool in retinal pigmented epithelial cells and mediates the mechanistic target of rapamycin, complex 1 signaling
por: Shang, Peng, et al.
Publicado: (2017)

Matrix Metalloproteinases in Age-Related Macular Degeneration (AMD)
por: García-Onrubia, Luis, et al.
Publicado: (2020)

Age-Related Macular Degeneration (AMD): A View to the Future
por: Miller, Joan W., et al.
Publicado: (2021)

Potential Therapeutic Candidates for Age-Related Macular Degeneration (AMD)
por: Nashine, Sonali
Publicado: (2021)

Artificial Intelligence to Stratify Severity of Age-Related Macular Degeneration (AMD) and Predict Risk of Progression to Late AMD
por: Bhuiyan, Alauddin, et al.
Publicado: (2020)

Sex Differences in RANTES (CCL5) in Patients With Intermediate Age-Related Macular Degeneration (AMD) and Controls With no AMD
por: Fonteh, Cheryl N., et al.
Publicado: (2022)

Age-Related Macular Degeneration: New Paradigms for Treatment and Management of AMD
por: Hernández-Zimbrón, Luis Fernando, et al.
Publicado: (2018)

Brolucizumab and fluid in neovascular age-related macular degeneration (n-AMD)
por: Sharma, Ashish, et al.
Publicado: (2020)

Linking Adiponectin and Its Receptors to Age-Related Macular Degeneration (AMD)
por: Choubey, Mayank, et al.
Publicado: (2023)

Initial non-responders to ranibizumab in the treatment of age-related macular degeneration (AMD)
por: Otsuji, Tsuyoshi, et al.
Publicado: (2013)

New and Innovative Treatments for Neovascular Age-Related Macular Degeneration (nAMD)
por: Patel, Prem, et al.
Publicado: (2021)

Effect of Humanin G (HNG) on inflammation in age-related macular degeneration (AMD)
por: Nashine, Sonali, et al.
Publicado: (2022)

Current barriers to treatment for wet age-related macular degeneration (wAMD): findings from the wAMD patient and caregiver survey
por: Varano, Monica, et al.
Publicado: (2015)

Monitoring for neovascular age-related macular degeneration (AMD) reactivation at home: the MONARCH study
por: Ward, Elizabeth, et al.
Publicado: (2020)

Prevalence of Geographic Atrophy in Advanced Age-Related Macular Degeneration (AMD) in Daily Practice
por: Abdin, Alaa Din, et al.
Publicado: (2023)

Activated cGAS/STING signaling elicits endothelial cell senescence in early diabetic retinopathy
por: Liu, Haitao, et al.
Publicado: (2023)

Mechanistic Insight into Age-Related Macular Degeneration (AMD): Anatomy, Epidemiology, Genetics, Pathogenesis, Prevention, Implications, and Treatment Strategies to Pace AMD Management
por: Amini, Mohammad Amin, et al.
Publicado: (2023)

What effects has the cataract surgery on the development and progression of Age-Related Macular Degeneration (AMD)?
por: Bockelbrink, Angelina, et al.
Publicado: (2006)

The effect of CFH polymorphisms on the response to the treatment of age-related macular degeneration (AMD) with intravitreal ranibizumab
por: Dikmetas, Ozlem, et al.
Publicado: (2013)

Epidemiology of age-related macular degeneration (AMD): associations with cardiovascular disease phenotypes and lipid factors
por: Pennington, Katie L., et al.
Publicado: (2016)

Role of Mitochondrial DNA Damage in ROS-Mediated Pathogenesis of Age-Related Macular Degeneration (AMD)
por: Kaarniranta, Kai, et al.
Publicado: (2019)

Inner blood-retina barrier involvement in dry age-related macular degeneration (AMD) pathology
por: Hudson, Natalie, et al.
Publicado: (2020)

Potential Role of Myeloid-Derived Suppressor Cells (MDSCs) in Age-Related Macular Degeneration (AMD)
por: Kauppinen, Anu, et al.
Publicado: (2020)

Ocular Therapeutics and Molecular Delivery Strategies for Neovascular Age-Related Macular Degeneration (nAMD)
por: Sarkar, Aira, et al.
Publicado: (2021)

Neovascular Age-Related Macular Degeneration (nAMD): A Review of Emerging Treatment Options
por: Tan, Colin S, et al.
Publicado: (2022)

Potential Sources and Roles of Adaptive Immunity in Age-Related Macular Degeneration: Shall We Rename AMD into Autoimmune Macular Disease?
por: Camelo, Serge
Publicado: (2014)

Evaluating Potential Therapies in a Mouse Model of Focal Retinal Degeneration with Age-related Macular Degeneration (AMD)-Like Lesions
por: Popp, Nicholas, et al.
Publicado: (2013)

Lysosomal-mediated waste clearance in retinal pigment epithelial cells is regulated by CRYBA1/βA3/A1-crystallin via V-ATPase-MTORC1 signaling
por: Valapala, Mallika, et al.
Publicado: (2014)

Role of antioxidant enzymes and small molecular weight antioxidants in the pathogenesis of age-related macular degeneration (AMD)
por: Tokarz, Paulina, et al.
Publicado: (2013)

Cannot write session to /tmp/vufind_sessions/sess_v4i6tfn1ash5rmd6f7a5qtbftg