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PEGylated human catalase elicits potent therapeutic effects on H1N1 influenza-induced pneumonia in mice

Therapeutic recombinant human catalase (rhCAT) can quench infection-induced reactive oxygen species (ROS), thereby alleviating the associated tissue damage. Although the intranasal route is efficient to deliver native rhCAT to the lung, the therapeutic effect is limited by rapid elimination from the...

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Detalles Bibliográficos
Autores principales:	Shi, Xunlong, Shi, Zhihui, Huang, Hai, Zhu, Hongguang, Zhu, Haiyan, Ju, Dianwen, Zhou, Pei
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Springer Berlin Heidelberg 2013
Materias:	Biotechnologically Relevant Enzymes and Proteins
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7079947/ https://www.ncbi.nlm.nih.gov/pubmed/23525936 http://dx.doi.org/10.1007/s00253-013-4775-3

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