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The novel amidocarbamate derivatives of ketoprofen: synthesis and biological activity

A series of novel ketoprofen derivatives 4a–j bearing both amide and carbamate functionalities were prepared using the benzotriazole method of carboxylic and hydroxy group activation. Selective reduction of ketoprofen produced hydroxy derivative 2, which in the reaction with one or two moles of 1-be...

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Detalles Bibliográficos
Autores principales: Rajić, Zrinka, Hadjipavlou-Litina, Dimitra, Pontiki, Eleni, Balzarini, Jan, Zorc, Branka
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer-Verlag 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7079954/
https://www.ncbi.nlm.nih.gov/pubmed/32214761
http://dx.doi.org/10.1007/s00044-010-9309-2