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The novel amidocarbamate derivatives of ketoprofen: synthesis and biological activity
A series of novel ketoprofen derivatives 4a–j bearing both amide and carbamate functionalities were prepared using the benzotriazole method of carboxylic and hydroxy group activation. Selective reduction of ketoprofen produced hydroxy derivative 2, which in the reaction with one or two moles of 1-be...
Autores principales: | Rajić, Zrinka, Hadjipavlou-Litina, Dimitra, Pontiki, Eleni, Balzarini, Jan, Zorc, Branka |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Springer-Verlag
2010
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7079954/ https://www.ncbi.nlm.nih.gov/pubmed/32214761 http://dx.doi.org/10.1007/s00044-010-9309-2 |
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