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Synthesis of novel N-acyl-β-d-glucopyranosylamines and ureas as potential lead cytostatic agents

Novel classes of acetylated and fully deprotected N-acyl-β-d-glucopyranosylamines and ureas have been synthesized and biologically evaluated. Acylation of the per-O-acetylated β-d-glucopyranosylurea (5), easily prepared via its corresponding phosphinimine derivative, by zinc chloride catalyzed react...

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Detalles Bibliográficos
Autores principales: Parmenopoulou, Vanessa, Manta, Stella, Dimopoulou, Athina, Kollatos, Nikolaos, Schols, Dominique, Komiotis, Dimitri
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer US 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7079967/
https://www.ncbi.nlm.nih.gov/pubmed/32214768
http://dx.doi.org/10.1007/s00044-016-1539-5

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