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(18)F-FDG PET/CT findings of COVID-19: a series of four highly suspected cases
PURPOSE: The aim of this case series is to illustrate the (18)F-FDG PET/CT findings of patients with acute respiratory disease caused by COVID-19 in Wuhan, Hubei province of China. METHODS: We describe the (18)F-FDG PET/CT results from four patients who were admitted to the hospital with respiratory...
Autores principales: | , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Springer Berlin Heidelberg
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7080035/ https://www.ncbi.nlm.nih.gov/pubmed/32088847 http://dx.doi.org/10.1007/s00259-020-04734-w |
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author | Qin, Chunxia Liu, Fang Yen, Tzu-Chen Lan, Xiaoli |
author_facet | Qin, Chunxia Liu, Fang Yen, Tzu-Chen Lan, Xiaoli |
author_sort | Qin, Chunxia |
collection | PubMed |
description | PURPOSE: The aim of this case series is to illustrate the (18)F-FDG PET/CT findings of patients with acute respiratory disease caused by COVID-19 in Wuhan, Hubei province of China. METHODS: We describe the (18)F-FDG PET/CT results from four patients who were admitted to the hospital with respiratory symptoms and fever between January 13 and January 20, 2020, when the COVID-19 outbreak was still unrecognized and the virus infectivity was unknown. A retrospective review of the patients’ medical history, clinical and laboratory data, as well as imaging findings strongly suggested a diagnosis of COVID-19. RESULTS: All patients had peripheral ground-glass opacities and/or lung consolidations in more than two pulmonary lobes. Lung lesions were characterized by a high (18)F-FDG uptake and there was evidence of lymph node involvement. Conversely, disseminated disease was absent, a finding suggesting that COVID-19 has pulmonary tropism. CONCLUSIONS: Although (18)F-FDG PET/CT cannot be routinely used in an emergency setting and is generally not recommended for infectious diseases, our pilot data shed light on the potential clinical utility of this imaging technique in the differential diagnosis of complex cases. |
format | Online Article Text |
id | pubmed-7080035 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2020 |
publisher | Springer Berlin Heidelberg |
record_format | MEDLINE/PubMed |
spelling | pubmed-70800352020-03-23 (18)F-FDG PET/CT findings of COVID-19: a series of four highly suspected cases Qin, Chunxia Liu, Fang Yen, Tzu-Chen Lan, Xiaoli Eur J Nucl Med Mol Imaging Short Communication PURPOSE: The aim of this case series is to illustrate the (18)F-FDG PET/CT findings of patients with acute respiratory disease caused by COVID-19 in Wuhan, Hubei province of China. METHODS: We describe the (18)F-FDG PET/CT results from four patients who were admitted to the hospital with respiratory symptoms and fever between January 13 and January 20, 2020, when the COVID-19 outbreak was still unrecognized and the virus infectivity was unknown. A retrospective review of the patients’ medical history, clinical and laboratory data, as well as imaging findings strongly suggested a diagnosis of COVID-19. RESULTS: All patients had peripheral ground-glass opacities and/or lung consolidations in more than two pulmonary lobes. Lung lesions were characterized by a high (18)F-FDG uptake and there was evidence of lymph node involvement. Conversely, disseminated disease was absent, a finding suggesting that COVID-19 has pulmonary tropism. CONCLUSIONS: Although (18)F-FDG PET/CT cannot be routinely used in an emergency setting and is generally not recommended for infectious diseases, our pilot data shed light on the potential clinical utility of this imaging technique in the differential diagnosis of complex cases. Springer Berlin Heidelberg 2020-02-22 2020 /pmc/articles/PMC7080035/ /pubmed/32088847 http://dx.doi.org/10.1007/s00259-020-04734-w Text en © Springer-Verlag GmbH Germany, part of Springer Nature 2020 This article is made available via the PMC Open Access Subset for unrestricted research re-use and secondary analysis in any form or by any means with acknowledgement of the original source. These permissions are granted for the duration of the World Health Organization (WHO) declaration of COVID-19 as a global pandemic. |
spellingShingle | Short Communication Qin, Chunxia Liu, Fang Yen, Tzu-Chen Lan, Xiaoli (18)F-FDG PET/CT findings of COVID-19: a series of four highly suspected cases |
title | (18)F-FDG PET/CT findings of COVID-19: a series of four highly suspected cases |
title_full | (18)F-FDG PET/CT findings of COVID-19: a series of four highly suspected cases |
title_fullStr | (18)F-FDG PET/CT findings of COVID-19: a series of four highly suspected cases |
title_full_unstemmed | (18)F-FDG PET/CT findings of COVID-19: a series of four highly suspected cases |
title_short | (18)F-FDG PET/CT findings of COVID-19: a series of four highly suspected cases |
title_sort | (18)f-fdg pet/ct findings of covid-19: a series of four highly suspected cases |
topic | Short Communication |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7080035/ https://www.ncbi.nlm.nih.gov/pubmed/32088847 http://dx.doi.org/10.1007/s00259-020-04734-w |
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