Current trends in targeted therapy for drug-resistant infections

Escalating antibiotic resistance is now a serious menace to global public health. It may be led to the emergence of “postantibiotic age” in which most of infections are untreatable. At present, there is an essential need to explore novel therapeutic strategies as a strong and sustainable pipeline to...

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Detalles Bibliográficos
Autores principales: Rahbarnia, Leila, Farajnia, Safar, Naghili, Behrooz, Ahmadzadeh, Vahideh, Veisi, Kamal, Baghban, Roghayyeh, Toraby, Sayna
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Berlin Heidelberg 2019
Materias:
Mini-Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7080082/
https://www.ncbi.nlm.nih.gov/pubmed/31414162
http://dx.doi.org/10.1007/s00253-019-10028-5
Descripción
Sumario:Escalating antibiotic resistance is now a serious menace to global public health. It may be led to the emergence of “postantibiotic age” in which most of infections are untreatable. At present, there is an essential need to explore novel therapeutic strategies as a strong and sustainable pipeline to combat antibiotic-resistant infections. This review focuses on recent advances in this area including therapeutic antibodies, antimicrobial peptides, vaccines, gene therapy, genome editing, and phage therapy for tackling drug-resistant infections.

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