Current trends in targeted therapy for drug-resistant infections

Escalating antibiotic resistance is now a serious menace to global public health. It may be led to the emergence of “postantibiotic age” in which most of infections are untreatable. At present, there is an essential need to explore novel therapeutic strategies as a strong and sustainable pipeline to...

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Detalles Bibliográficos
Autores principales: Rahbarnia, Leila, Farajnia, Safar, Naghili, Behrooz, Ahmadzadeh, Vahideh, Veisi, Kamal, Baghban, Roghayyeh, Toraby, Sayna
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Berlin Heidelberg 2019
Materias:
Mini-Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7080082/
https://www.ncbi.nlm.nih.gov/pubmed/31414162
http://dx.doi.org/10.1007/s00253-019-10028-5
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author Rahbarnia, Leila
Farajnia, Safar
Naghili, Behrooz
Ahmadzadeh, Vahideh
Veisi, Kamal
Baghban, Roghayyeh
Toraby, Sayna
author_facet Rahbarnia, Leila
Farajnia, Safar
Naghili, Behrooz
Ahmadzadeh, Vahideh
Veisi, Kamal
Baghban, Roghayyeh
Toraby, Sayna
author_sort Rahbarnia, Leila
collection PubMed
description Escalating antibiotic resistance is now a serious menace to global public health. It may be led to the emergence of “postantibiotic age” in which most of infections are untreatable. At present, there is an essential need to explore novel therapeutic strategies as a strong and sustainable pipeline to combat antibiotic-resistant infections. This review focuses on recent advances in this area including therapeutic antibodies, antimicrobial peptides, vaccines, gene therapy, genome editing, and phage therapy for tackling drug-resistant infections.
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spelling pubmed-70800822020-03-23 Current trends in targeted therapy for drug-resistant infections Rahbarnia, Leila Farajnia, Safar Naghili, Behrooz Ahmadzadeh, Vahideh Veisi, Kamal Baghban, Roghayyeh Toraby, Sayna Appl Microbiol Biotechnol Mini-Review Escalating antibiotic resistance is now a serious menace to global public health. It may be led to the emergence of “postantibiotic age” in which most of infections are untreatable. At present, there is an essential need to explore novel therapeutic strategies as a strong and sustainable pipeline to combat antibiotic-resistant infections. This review focuses on recent advances in this area including therapeutic antibodies, antimicrobial peptides, vaccines, gene therapy, genome editing, and phage therapy for tackling drug-resistant infections. Springer Berlin Heidelberg 2019-08-14 2019 /pmc/articles/PMC7080082/ /pubmed/31414162 http://dx.doi.org/10.1007/s00253-019-10028-5 Text en © Springer-Verlag GmbH Germany, part of Springer Nature 2019 This article is made available via the PMC Open Access Subset for unrestricted research re-use and secondary analysis in any form or by any means with acknowledgement of the original source. These permissions are granted for the duration of the World Health Organization (WHO) declaration of COVID-19 as a global pandemic.
spellingShingle Mini-Review
Rahbarnia, Leila
Farajnia, Safar
Naghili, Behrooz
Ahmadzadeh, Vahideh
Veisi, Kamal
Baghban, Roghayyeh
Toraby, Sayna
Current trends in targeted therapy for drug-resistant infections
title Current trends in targeted therapy for drug-resistant infections
title_full Current trends in targeted therapy for drug-resistant infections
title_fullStr Current trends in targeted therapy for drug-resistant infections
title_full_unstemmed Current trends in targeted therapy for drug-resistant infections
title_short Current trends in targeted therapy for drug-resistant infections
title_sort current trends in targeted therapy for drug-resistant infections
topic Mini-Review
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7080082/
https://www.ncbi.nlm.nih.gov/pubmed/31414162
http://dx.doi.org/10.1007/s00253-019-10028-5
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