CD147 promotes IKK/IκB/NF-κB pathway to resist TNF-induced apoptosis in rheumatoid arthritis synovial fibroblasts

ABSTRACT: TNF is highly expressed in synovial tissue of rheumatoid arthritis (RA) patients, where it induces proinflammatory cytokine secretion. However, in other cases, TNF will cause cell death. Considering the abnormal proliferation and activation of rheumatoid arthritis synovioblasts, the proper...

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Detalles Bibliográficos
Autores principales: Zhai, Yue, Wu, Bo, Li, Jia, Yao, Xi-ying, Zhu, Ping, Chen, Zhi-nan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Berlin Heidelberg 2015
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7080145/
https://www.ncbi.nlm.nih.gov/pubmed/26296700
http://dx.doi.org/10.1007/s00109-015-1334-7

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7080145/
https://www.ncbi.nlm.nih.gov/pubmed/26296700
http://dx.doi.org/10.1007/s00109-015-1334-7

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