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Frontiers in Molecular Evolutionary Medicine
This paper surveys some of the important insights that molecular evolution has contributed to evolutionary medicine; they include phage therapy, cancer biology, helminth manipulation of the host immune system, quality control of gametes, and pathogen outbreaks. Molecular evolution has helped to revo...
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Formato: | Online Artículo Texto |
Lenguaje: | English |
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Springer US
2019
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7080150/ https://www.ncbi.nlm.nih.gov/pubmed/30968167 http://dx.doi.org/10.1007/s00239-019-09893-5 |
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author | Stearns, Stephen C. |
author_facet | Stearns, Stephen C. |
author_sort | Stearns, Stephen C. |
collection | PubMed |
description | This paper surveys some of the important insights that molecular evolution has contributed to evolutionary medicine; they include phage therapy, cancer biology, helminth manipulation of the host immune system, quality control of gametes, and pathogen outbreaks. Molecular evolution has helped to revolutionize our understanding of cancer, of autoimmune disease, and of the origin, spread, and pathogenesis of emerging diseases, where it has suggested new therapies, illuminated mechanisms, and revealed historical processes: all have practical therapeutic implications. While much has been accomplished, much remains to be done. |
format | Online Article Text |
id | pubmed-7080150 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2019 |
publisher | Springer US |
record_format | MEDLINE/PubMed |
spelling | pubmed-70801502020-03-23 Frontiers in Molecular Evolutionary Medicine Stearns, Stephen C. J Mol Evol Review This paper surveys some of the important insights that molecular evolution has contributed to evolutionary medicine; they include phage therapy, cancer biology, helminth manipulation of the host immune system, quality control of gametes, and pathogen outbreaks. Molecular evolution has helped to revolutionize our understanding of cancer, of autoimmune disease, and of the origin, spread, and pathogenesis of emerging diseases, where it has suggested new therapies, illuminated mechanisms, and revealed historical processes: all have practical therapeutic implications. While much has been accomplished, much remains to be done. Springer US 2019-04-09 2020 /pmc/articles/PMC7080150/ /pubmed/30968167 http://dx.doi.org/10.1007/s00239-019-09893-5 Text en © Springer Science+Business Media, LLC, part of Springer Nature 2019 This article is made available via the PMC Open Access Subset for unrestricted research re-use and secondary analysis in any form or by any means with acknowledgement of the original source. These permissions are granted for the duration of the World Health Organization (WHO) declaration of COVID-19 as a global pandemic. |
spellingShingle | Review Stearns, Stephen C. Frontiers in Molecular Evolutionary Medicine |
title | Frontiers in Molecular Evolutionary Medicine |
title_full | Frontiers in Molecular Evolutionary Medicine |
title_fullStr | Frontiers in Molecular Evolutionary Medicine |
title_full_unstemmed | Frontiers in Molecular Evolutionary Medicine |
title_short | Frontiers in Molecular Evolutionary Medicine |
title_sort | frontiers in molecular evolutionary medicine |
topic | Review |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7080150/ https://www.ncbi.nlm.nih.gov/pubmed/30968167 http://dx.doi.org/10.1007/s00239-019-09893-5 |
work_keys_str_mv | AT stearnsstephenc frontiersinmolecularevolutionarymedicine |