Large-scale generation of functional mRNA-encapsulating exosomes via cellular nanoporation

Exosomes are attractive nucleic-acid carriers because of their favourable pharmacokinetic and immunological properties and of their ability to penetrate physiological barriers that are impermissible to synthetic drug-delivery vehicles. However, inserting exogenous nucleic acids, especially large mes...

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Detalles Bibliográficos
Autores principales: Yang, Zhaogang, Shi, Junfeng, Xie, Jing, Wang, Yifan, Sun, Jingyao, Liu, Tongzheng, Zhao, Yarong, Zhao, Xiuting, Wang, Xinmei, Ma, Yifan, Malkoc, Veysi, Chiang, Chiling, Deng, Weiye, Chen, Yuanxin, Fu, Yuan, Kwak, Kwang J., Fan, Yamin, Kang, Chen, Yin, Changcheng, Rhee, June, Bertani, Paul, Otero, Jose, Lu, Wu, Yun, Kyuson, Lee, Andrew S., Jiang, Wen, Teng, Lesheng, Kim, Betty Y.S., Lee, L. James
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7080209/
https://www.ncbi.nlm.nih.gov/pubmed/31844155
http://dx.doi.org/10.1038/s41551-019-0485-1

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