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Clinical recommendations to guide physical therapy practice for Huntington disease
OBJECTIVE: In the past decade, an increasing number of studies have examined the efficacy of physical therapy interventions in people with Huntington disease (HD). METHODS: We performed a mixed-methods systematic review using Joanna Briggs Institute (JBI) methodology and included experimental and ob...
Autores principales: | , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
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Lippincott Williams & Wilkins
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7080285/ https://www.ncbi.nlm.nih.gov/pubmed/31907286 http://dx.doi.org/10.1212/WNL.0000000000008887 |
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author | Quinn, Lori Kegelmeyer, Deb Kloos, Anne Rao, Ashwini K. Busse, Monica Fritz, Nora E. |
author_facet | Quinn, Lori Kegelmeyer, Deb Kloos, Anne Rao, Ashwini K. Busse, Monica Fritz, Nora E. |
author_sort | Quinn, Lori |
collection | PubMed |
description | OBJECTIVE: In the past decade, an increasing number of studies have examined the efficacy of physical therapy interventions in people with Huntington disease (HD). METHODS: We performed a mixed-methods systematic review using Joanna Briggs Institute (JBI) methodology and included experimental and observational study designs. The search resulted in 23 quantitative studies and 3 qualitative studies from which we extracted data using JBI standardized extraction tools. Results of this review suggested that physical therapy interventions may improve motor impairments and activity limitations in people with HD. Here, we expand on the review findings to provide specific recommendations to guide clinical practice. RESULTS: We recommend the following specific physical therapy interventions for people with HD: aerobic exercise (grade A evidence), alone or in combination with resistance training to improve fitness and motor function, and supervised gait training (grade A evidence) to improve spatiotemporal features of gait. In addition, there is weak (grade B) evidence that exercise training improves balance but does not show a reduction in the frequency of falls; inspiratory and expiratory training improves breathing function and capacity; and training of transfers, getting up from the floor, and providing strategies to caregivers for involvement in physical activity in the midstages of HD may improve performance. There is expert consensus for the use of positioning devices, seating adaptations, and caregiver training in late stages of HD. CONCLUSIONS: There is strong evidence to support physical therapy interventions to improve fitness, motor function, and gait in persons with HD. |
format | Online Article Text |
id | pubmed-7080285 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2020 |
publisher | Lippincott Williams & Wilkins |
record_format | MEDLINE/PubMed |
spelling | pubmed-70802852020-03-25 Clinical recommendations to guide physical therapy practice for Huntington disease Quinn, Lori Kegelmeyer, Deb Kloos, Anne Rao, Ashwini K. Busse, Monica Fritz, Nora E. Neurology Views & Reviews OBJECTIVE: In the past decade, an increasing number of studies have examined the efficacy of physical therapy interventions in people with Huntington disease (HD). METHODS: We performed a mixed-methods systematic review using Joanna Briggs Institute (JBI) methodology and included experimental and observational study designs. The search resulted in 23 quantitative studies and 3 qualitative studies from which we extracted data using JBI standardized extraction tools. Results of this review suggested that physical therapy interventions may improve motor impairments and activity limitations in people with HD. Here, we expand on the review findings to provide specific recommendations to guide clinical practice. RESULTS: We recommend the following specific physical therapy interventions for people with HD: aerobic exercise (grade A evidence), alone or in combination with resistance training to improve fitness and motor function, and supervised gait training (grade A evidence) to improve spatiotemporal features of gait. In addition, there is weak (grade B) evidence that exercise training improves balance but does not show a reduction in the frequency of falls; inspiratory and expiratory training improves breathing function and capacity; and training of transfers, getting up from the floor, and providing strategies to caregivers for involvement in physical activity in the midstages of HD may improve performance. There is expert consensus for the use of positioning devices, seating adaptations, and caregiver training in late stages of HD. CONCLUSIONS: There is strong evidence to support physical therapy interventions to improve fitness, motor function, and gait in persons with HD. Lippincott Williams & Wilkins 2020-02-04 /pmc/articles/PMC7080285/ /pubmed/31907286 http://dx.doi.org/10.1212/WNL.0000000000008887 Text en Copyright © 2020 The Author(s). Published by Wolters Kluwer Health, Inc. on behalf of the American Academy of Neurology. https://creativecommons.org/licenses/by-nc-nd/4.0/This is an open access article distributed under the terms of the Creative Commons Attribution-NonCommercial-NoDerivatives License 4.0 (CC BY-NC-ND) (https://creativecommons.org/licenses/by-nc-nd/4.0/) , which permits downloading and sharing the work provided it is properly cited. The work cannot be changed in any way or used commercially without permission from the journal. |
spellingShingle | Views & Reviews Quinn, Lori Kegelmeyer, Deb Kloos, Anne Rao, Ashwini K. Busse, Monica Fritz, Nora E. Clinical recommendations to guide physical therapy practice for Huntington disease |
title | Clinical recommendations to guide physical therapy practice for Huntington disease |
title_full | Clinical recommendations to guide physical therapy practice for Huntington disease |
title_fullStr | Clinical recommendations to guide physical therapy practice for Huntington disease |
title_full_unstemmed | Clinical recommendations to guide physical therapy practice for Huntington disease |
title_short | Clinical recommendations to guide physical therapy practice for Huntington disease |
title_sort | clinical recommendations to guide physical therapy practice for huntington disease |
topic | Views & Reviews |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7080285/ https://www.ncbi.nlm.nih.gov/pubmed/31907286 http://dx.doi.org/10.1212/WNL.0000000000008887 |
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