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Metabolomics analysis reveals perturbations of cerebrocortical metabolic pathways in the Pah(enu2) mouse model of phenylketonuria

AIMS: Phenylketonuria (PKU), which is caused by mutations in the phenylalanine hydroxylase (PAH) gene, is one of the most common inherited diseases of amino acid metabolism. Phenylketonuria is characterized by an abnormal accumulation of phenylalanine and its metabolites in body fluids and brain tis...

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Detalles Bibliográficos
Autores principales:	Lu, Li‐Hua, Xia, Zheng‐Xiang, Guo, Jia‐Lin, Xiao, Ling‐Ling, Zhang, Yong‐Jun
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	John Wiley and Sons Inc. 2019
Materias:	Original Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7080435/ https://www.ncbi.nlm.nih.gov/pubmed/31471952 http://dx.doi.org/10.1111/cns.13214

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