Tumor-Infiltrating T Cells From Clear Cell Renal Cell Carcinoma Patients Recognize Neoepitopes Derived From Point and Frameshift Mutations

Mutation-derived neoantigens are important targets for T cell-mediated reactivity toward tumors and, due to their unique tumor expression, an attractive target for immunotherapy. Neoepitope-specific T cells have been detected across a number of solid cancers with high mutational burden tumors, but n...

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Detalles Bibliográficos
Autores principales: Hansen, Ulla Kring, Ramskov, Sofie, Bjerregaard, Anne-Mette, Borch, Annie, Andersen, Rikke, Draghi, Arianna, Donia, Marco, Bentzen, Amalie Kai, Marquard, Andrea Marion, Szallasi, Zoltan, Eklund, Aron Charles, Svane, Inge Marie, Hadrup, Sine Reker
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2020
Materias:
Immunology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7080703/
https://www.ncbi.nlm.nih.gov/pubmed/32226429
http://dx.doi.org/10.3389/fimmu.2020.00373

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7080703/
https://www.ncbi.nlm.nih.gov/pubmed/32226429
http://dx.doi.org/10.3389/fimmu.2020.00373

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