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RAB5A and TRAPPC6B are novel targets for Shiga toxin 2a inactivation in kidney epithelial cells

The cardinal virulence factor of human-pathogenic enterohaemorrhagic Escherichia coli (EHEC) is Shiga toxin (Stx), which causes severe extraintestinal complications including kidney failure by damaging renal endothelial cells. In EHEC pathogenesis, the disturbance of the kidney epithelium by Stx bec...

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Detalles Bibliográficos
Autores principales:	Kouzel, Ivan U., Kehl, Alexander, Berger, Petya, Liashkovich, Ivan, Steil, Daniel, Makalowski, Wojciech, Suzuki, Yutaka, Pohlentz, Gottfried, Karch, Helge, Mellmann, Alexander, Müthing, Johannes
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2020
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7080763/ https://www.ncbi.nlm.nih.gov/pubmed/32188865 http://dx.doi.org/10.1038/s41598-020-59694-w

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