Filamentation of the bacterial bi-functional alcohol/aldehyde dehydrogenase AdhE is essential for substrate channeling and enzymatic regulation

Acetaldehyde–alcohol dehydrogenase (AdhE) enzymes are a key metabolic enzyme in bacterial physiology and pathogenicity. They convert acetyl-CoA to ethanol via an acetaldehyde intermediate during ethanol fermentation in an anaerobic environment. This two-step reaction is associated to NAD(+) regenera...

Descripción completa

Detalles Bibliográficos
Autores principales: Pony, Pauline, Rapisarda, Chiara, Terradot, Laurent, Marza, Esther, Fronzes, Rémi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7080775/
https://www.ncbi.nlm.nih.gov/pubmed/32188856
http://dx.doi.org/10.1038/s41467-020-15214-y

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7080775/
https://www.ncbi.nlm.nih.gov/pubmed/32188856
http://dx.doi.org/10.1038/s41467-020-15214-y

Ejemplares similares