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ecTMB: a robust method to estimate and classify tumor mutational burden

Tumor Mutational Burden (TMB) is a measure of the abundance of somatic mutations in a tumor, which has been shown to be an emerging biomarker for both anti-PD-(L)1 treatment and prognosis; however, multiple challenges still hinder the adoption of TMB as a biomarker. The key challenges are the incons...

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Detalles Bibliográficos
Autores principales: Yao, Lijing, Fu, Yao, Mohiyuddin, Marghoob, Lam, Hugo Y. K.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7080796/
https://www.ncbi.nlm.nih.gov/pubmed/32188929
http://dx.doi.org/10.1038/s41598-020-61575-1

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