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Impaired bile acid metabolism with defectives of mitochondrial-tRNA taurine modification and bile acid taurine conjugation in the taurine depleted cats
Taurine that conjugates with bile acid (BA) and mitochondrial-tRNA (mt-tRNA) is a conditional essential amino acid in humans, similarly to cats. To better understand the influence of acquired depletion of taurine on BA metabolism, the profiling of BAs and its intermediates, BA metabolism-enzyme expr...
Autores principales: | Miyazaki, Teruo, Sasaki, Sei-Ich, Toyoda, Atsushi, Wei, Fan-Yan, Shirai, Mutsumi, Morishita, Yukio, Ikegami, Tadashi, Tomizawa, Kazuhito, Honda, Akira |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7080809/ https://www.ncbi.nlm.nih.gov/pubmed/32188916 http://dx.doi.org/10.1038/s41598-020-61821-6 |
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