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Sex Differences in Associations Between CYP2D6 Phenotypes and Response to Opioid Analgesics
BACKGROUND: Several small studies have previously investigated associations between the cytochrome P450 2D6 (CYP2D6) metabolism and response to opioids. We used a large sample of patients to study associations between CYP2D6 phenotypes and estimated CYP2D6 enzymatic activity scores with pain control...
Autores principales: | Lopes, Guilherme S, Bielinski, Suzette J, Moyer, Ann M, Black III, John Logan, Jacobson, Debra J, Jiang, Ruoxiang, Larson, Nicholas B, St Sauver, Jennifer L |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Dove
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7081062/ https://www.ncbi.nlm.nih.gov/pubmed/32214840 http://dx.doi.org/10.2147/PGPM.S239222 |
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