An Exploratory Phase IIa Study of the PPAR delta/gamma Agonist T3D-959 Assessing Metabolic and Cognitive Function in Subjects with Mild to Moderate Alzheimer’s Disease

BACKGROUND: T3D-959 is a chemically unique, brain penetrant, dual PPAR delta/gamma agonist with 15-fold higher PPAR delta selectivity. Ubiquitous brain expression of PPAR delta, its critical role in regulating glucose and lipid metabolism, and the Alzheimer’s disease (AD)-like phenotype of PPAR delt...

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Detalles Bibliográficos
Autores principales: Chamberlain, Stanley, Gabriel, Hoda, Strittmatter, Warren, Didsbury, John
Formato: Online Artículo Texto
Lenguaje:English
Publicado: IOS Press 2020
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7081093/
https://www.ncbi.nlm.nih.gov/pubmed/31884472
http://dx.doi.org/10.3233/JAD-190864

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7081093/
https://www.ncbi.nlm.nih.gov/pubmed/31884472
http://dx.doi.org/10.3233/JAD-190864

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