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Nuclear receptor CAR-ERα signaling regulates the estrogen sulfotransferase gene in the liver

Estrogen sulfotransferase (SULT1E1) inactivates estrogen and regulates its metabolic homeostats. Whereas SULT1E1 is expressed low in the liver of adult mice, it is induced by phenobarbital (PB) treatment or spontaneously in diabetic livers via nuclear receptors. Utilizing constitutive active/androst...

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Detalles Bibliográficos
Autores principales:	Yi, MyeongJin, Fashe, Muluneh, Arakawa, Shingo, Moore, Rick, Sueyoshi, Tatsuya, Negishi, Masahiko
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2020
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7081254/ https://www.ncbi.nlm.nih.gov/pubmed/32193417 http://dx.doi.org/10.1038/s41598-020-61767-9

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