Cargando…
Proximal C-Terminus Serves as a Signaling Hub for TRPA1 Channel Regulation via Its Interacting Molecules and Supramolecular Complexes
Our understanding of the general principles of the polymodal regulation of transient receptor potential (TRP) ion channels has grown impressively in recent years as a result of intense efforts in protein structure determination by cryo-electron microscopy. In particular, the high-resolution structur...
Autores principales: | Zimova, Lucie, Barvikova, Kristyna, Macikova, Lucie, Vyklicka, Lenka, Sinica, Viktor, Barvik, Ivan, Vlachova, Viktorie |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2020
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7081373/ https://www.ncbi.nlm.nih.gov/pubmed/32226391 http://dx.doi.org/10.3389/fphys.2020.00189 |
Ejemplares similares
-
Human and Mouse TRPA1 Are Heat and Cold Sensors Differentially Tuned by Voltage
por: Sinica, Viktor, et al.
Publicado: (2019) -
Phospho-Mimetic Mutation at Ser602 Inactivates Human TRPA1 Channel
por: Barvikova, Kristyna, et al.
Publicado: (2020) -
Cytoplasmic Inter-Subunit Interface Controls Use-Dependence of Thermal Activation of TRPV3 Channel
por: Macikova, Lucie, et al.
Publicado: (2019) -
The First Extracellular Linker Is Important for Several Aspects of the Gating Mechanism of Human TRPA1 Channel
por: Marsakova, Lenka, et al.
Publicado: (2017) -
The human TRPA1 intrinsic cold and heat sensitivity involves separate channel structures beyond the N-ARD domain
por: Moparthi, Lavanya, et al.
Publicado: (2022)